Open position for a PhD student in “Microbial Regulation of Intestinal Tumor Development” (m/f/d)

This position is offered within the Collaborative Research Centre (CRC) 1371 at the Center for Regenerative Therapies Dresden (Mucosal Immunology lab – PI: Prof. Sebastian Zeissig)

The gut microbiome plays a fundamental role in health and disease. CRC 1371 (Speaker Prof. Dr. Dirk Haller) focuses on the digestive tract and proposes an interdisciplinary approach to characterizing the functional relevance of microbiome signatures in the context of inflammation and cancer.

Activities and responsibilities

In this project, which will be conducted in the Mucosal Immunology Laboratory (PI: Prof. Sebastian Zeissig) at the Center for Regenerative Therapies Dresden (www.crt-dresden.de), we will study the role of microbial factors in the regulation of colorectal cancer development. Specifically, we aim to analyze whether particular microbial taxa are responsible for tumor-promoting compared to tumor-suppressive effects. Moreover, the molecular pathways involved in microbiota-dependent regulation of intestinal tumor development will be studied. Analyses will be performed in genetically engineered mouse models of intestinal tumor development, which have been rederived in a germ-free manner and will be exposed to human and murine cancer-associated bacterial taxa.

Qualification profile

Candidates hold a Master degree (or equivalent) in a field related to the topic, ideally have expertise in the work with mice, and have excellent command of the English language (oral and written).

Application
Applicants are asked to send one pdf file to the contact person. The file includes
  • cover letter,
  • curriculum vitae,
  • copies of academic degrees and transcripts of records,
  • contact information for at least one letter of recommendation,
  • list of publications

Benefits

Within CRC 1371, the Integrated Research Training School (IRTG) provides a qualification program for PhD students containing excellent multidisciplinary training with tailor-made subject-based and soft skills courses, annual retreats, summer school, and a supervision concept.
For more information on the IRTG, the research projects and principal investigators follow the link to the CRC 1371 website: sfb1371@tum.de.

Salary and duration
Payment is according to the wage agreement of the civil service TV-L, 65% of E13 for PhD student positions.

Send application to

Prof. Sebastian Zeissig
Email: sebastian.zeissig@tu-dresden.de

While applying for the job please refer to jobvector

About Technical University of Munich

The CRC 1371 (Speaker Prof. Dr. Dirk Haller, Department of Nutrition and Immunology, Technical University of Munich) is a DFG-funded Collaborative Research Centre with its hub at the Technical University of Munich, TUM School of Life Sciences Weihenstephan, TUM School of Medicine and at the Klinikum rechts der Isar. The consortium further exists of strong partners at European Molecular Biology...
More about Technical University of Munich