Activities and responsibilitiesWithin the project Identification and characterization of pruritus pathways in chronic skin inflammation is available at the Department of Human Medicine, Faculty 6, University of Oldenburg starting March 2019. The project is part of a DFG research group (FOR2690).
Chronic pruritus - a major clinical symptom in a variety of diseases - severely reduces quality of life and is particularly difficult to treat. Chronic inflammatory skin diseases, including lichen planus (LP), psoriasis (PSO) and atopic dermatitis, are a major cause of chronic pruritus.
In this project we will evaluate known -and identify novel- pruritic pathways. To this end we will apply transcriptome and cytokine profiling of skin infiltrating T cells, mast cells and eosinophils as well as peripheral blood mononuclear cells (PBMCs). Our systematic analysis of the molecular and cellular mechanisms underlying chronic pruritus during skin inflammation will guide the development of novel therapeutic approaches.
Qualification profileAn academic university degree (MSc or comparable qualification) in life science, biology, biochemistry, medicine or equivalent is required. Hands-on experience in molecular biological and biochemical methods is expected. English skills and hands-on experience in one or more of the following techniques would be an advantage: FACS, quantitative PCR, immunological methods (Western Blot, ELISA, antibody staining), fluorescence microscopy, next generation sequencing.
BenefitsThe University of Oldenburg is dedicated to increasing the percentage of female employees in the field of science and encourages applications from female candidates. According to § 21, 3 NHG female applicants are preferentially considered in case of equal qualification. Applicants with disabilities will be given preference provided they are equally qualified.
Send application toPlease send your application, preferably by e-mail, until January 31st, 2019 to
Univ.-Prof. Dr. Ulrike Raap, director
Division of Experimental Allergology and Immunodermatology
Department für Humanmedizin, Fakultät VI
Carl von Ossietzky Universität Oldenburg
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