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PhD position in Life sciences

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The Institute of Physiology I, University of Bonn Medical School, Germany invites candidates for a DFG-funded
 
PhD position (TV-L EG13, 65%)
 
The position starts as soon as possible and is funded for a period of 3 years.
 
The DFG-project entitled „Role of the Endocannabinoid Systems in airway tone regulation under physiological and pathophysiological conditions“ focuses on effects of endocannabinoids and their metabolites on airway regulation.
 
Our laboratory employs a wide array of experimental techniques including cell biology, molecular biology, protein biochemistry (cell culture work, lentiviral transduction, magnetic nanoparticles, qRT-PCR, Westen Blot analysis) and physiology (Ca2+ imaging, isometric force measurements, mouse spirometry, whole body plethysmography, pressure catheter measurements). Results are transferred to experimental mouse models of asthma and COPD.

The ideal candidate will be a highly motivated graduate with an university degree in (Veterinary)medicine, Biology, Biomedicine, Biochemistry or a related subject. She/he has a strong interest in application-oriented basic research and is willing to work with mice. Experience with cell biology, physiology and/or animal experimentation techniques is desired. Good English skills are expected.
 
The Institute of Physiology I is located in the Life & Brain Center of the University of Bonn with state-of-the-art equipment. We provide an excellent training and research infrastructure, supportive mentoring and a highly interactive and stimulating environment.
 
We offer salary according to the German salary scale TVL EG13, Jobticket and supplementary benefits in the public sector (pension plan according to VBL).
 
The University of Bonn is an equal opportunity employer.
Please submit your application (including CV, copies of your education certificates, a motivation letter, a brief summary of previous research experience, contact information of 2 referees) within the next 3 weeks via email in a single pdf file to:
 
Jun.-Prof. Dr. med. Daniela Wenzel
Institut für Physiologie I
Universitätsklinikum Bonn
e-mail: dwenzel@uni-bonn.de
 
 
 
Literature:
 
Wenzel D, Knies R, Matthey M, Klein AM, Welschoff J, Stolle V, Sasse P, Roell W, Breuer J, Fleischmann BK. The beta2-adrenoceptor antagonist ICI 118,551 decreases pulmonary vascular tone in mice via a Gi/o protein/nitric oxide-coupled pathway. Hypertension. 2009; 54:157-163
 
Wenzel D, Matthey M, Bindila L, Lerner R, Lutz B, Zimmer A, Fleischmann BK. Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18710-5.
 
Welschoff J, Matthey M, Wenzel D. RGD peptides induce relaxation of pulmonary arteries and airways via beta3-integrins. FASEB J. 2014 May; 28(5):2281-92.
 
 

Contact detail


How to apply:
per email
Send application to
Jun.-Prof. Dr. med. Daniela Wenzel
Institut für Physiologie I
Universitätsklinikum Bonn
e-mail: dwenzel@uni-bonn.de
 
 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Nordrhein-Westfalen)
Working place
53127 Bonn
Area of expertise
Human medicine, Biology & Life Sciences, Pharmaceutics, Veterinary Medicine
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