PhD positions in highly interdisciplinary consortium on the Physics of integrin adhesion

The Physics Department of the Technical University of Munich (http://www.bio.ph.tum.de) and the Department of Molecular Medicine at the Max Planck Institute of Biochemistry (http://www.biochem.mpg.de/faessler) have several job openings and are seeking to fill them with Biophysicists as well as Biochemists at the pre- as well as postdoctoral level. The successful candidates for these positions would take over an ambitious project in which reconstituted adhesion complexes are used to understand the earliest molecular events of cell adhesion to integrin substrates from the single molecule level up to the cellular level. Emphasis is to obtain a comprehensive quantitative physical understanding of the involved process. The project is funded by an ERC-Synergy grant over six years.

Activities and responsibilities

The candidates would join a successful and well-equipped consortium of three laboratories with world-wide recognition on the field of adhesion biology, cellular - and single molecule biophysics (Prof. Fässler - MPI, Prof. Bausch – TUM, Prof. Rief – TUM). Besides an interesting and disease-relevant project, we offer the opportunity to connect to internationally renowned scientists.

Qualification profile

  • High motivation, curiosity, and commitment to scientific excellence
  • Master's or PhD degree in physics, cell biology, biochemistry, biophysics or similar fields
  • Practical lab experience
  • Interest in interdisciplinary and quantitative biology
  • Excellent skills in spoken as well as written English

The successful candidates will have a strong background in either biochemistry, biophysics or physics, preferably with in depth experience in:
  • heterologous protein expression und purification
  • characterization of proteins Analysis of protein interactions (e.g. surface plasmon resonance, isothermal titration calorimetry, analytical ultracentrifugation, dynamic light scattering)
  • single molecule measurements
  • optical tweezers and experience with self built optical instruments
  • advanced methods of light microscopy and digital imaging processing and analysis
  • biomechanics and concepts of (bio) soft matter physics and active matter physics

Benefits

Remuneration and benefits are in accordance with the collective agreement for the public service (TVÖD). 
Please send your application (including motivation letter, CV, names of two referees and transcripts) as one PDF.

Send application to

Prof. Andreas Bausch
Technische Universität München
Physik-Department, Lehrstuhl für Zellbiophysik E27
James-Franck-Straße 1
85748 Garching
e27applications@ph.tum.de
www.bauschlab.com
http://bio.ph.tum.de/home/e22-prof-dr-rief/rief-home.html
https://www.biochem.mpg.de/en/rd/faessler

While applying for the job please refer to jobvector

About Technische Universität München

We are interested in the self organization processes which enable biology to form all the fascinating structures and functions, life depends on. Thereby, we concentrate on two major aspects: (i) the micro-mechanical and (ii) out of equilibrium properties of living systems. ​ One of our main focus is to reconstitute functional modules mimicking life-like properties. On that score we are...

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