Göttingen, Lower Saxony
The Fraunhofer-Gesellschaft (www.fraunhofer.com) currently operates 76 institutes and research institutions throughout Germany and is the world’s leading applied research organization. Around 30 800 employees work with an annual research budget of 3.0 billion euros.
The Fraunhofer branch »Translational Neuroinflammation and Automated Microscopy« in Göttingen is part of the Fraunhofer Institute for Translational Medicine and Pharmacology ITMP. Here, we focus on understanding pathological and immunological mechanisms in the development and progression of demyelinating diseases of the central nervous system.
Multiple Sclerosis is an inflammatory demyelinating disease of the central nervous system. For relapsing-remitting multiple sclerosis, major advances have been made in the development of various disease-modifying therapies that effectively reduce the number and severity of new relapses as well as MRI activity. During the progressive stages of multiple sclerosis, in which new lesions become less frequent and the progression is characterized by a steady increase in neurological disability, most of the drugs on the market are unable to prevent disease progression.
The aim of this study is to test suitable candidates for the treatment of progressive multiple sclerosis via animal models and in vitro analysis. For in vivo experiments, we will utilize the murine multiple sclerosis model for experimental autoimmune encephalomyelitis as well as the cuprizone-induced model of demyelination. For in vitro experiments, primary cell cultures of CNS-resident cells will be used. The main methods of this study will be among others flow cytometry, magnetic-activated cell sorting, ELISA, qPCR and immunohistology.
PhD students have the opportunity to participate in one of several PhD programs in collaboration with the University of Göttingen, where they will be able to present their work at conferences and publish their work in scientific journals. Through this close cooperation, participants have access to a wide range of techniques and facilities.
Highly motivated and have a strong interest to work at the interface between research, medicine, and industry. PhD-students furthermore:
Your professional qualifications are complemented by a quick grasp, structured and independent way of working and a good team spirit.
Questions to Position:
Prof. Martin Weber / Dr. Darius Häusler
Phone: +49 551 39-63658
If you have any questions about the application process, please contact
Dr. Ursula Wegenka
email
Phone: +49 551 39-65284
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
www.itmp.fraunhofer.de
Requisition Number: 72711
The weekly working time is 39 hours. This position is also available on a part-time basis. We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, romantic orientation and identity. Severely disabled persons are given preference in the event of equal suitability. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD).
With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.
Robert-Koch-Straße 40
37075 Göttingen
Lower Saxony
Germany